For defining the design service life of China double aisles widebody commercial aircraft, the global double aisles widebody commercial aircraft airlines are researched and analyzed. Through collecting and classifying the double aisles widebody commercial aircraft airlines data, the primary effect factors are provided and classified. With considering different effect factors, especially the factor of “potential customers”, the widebody commercial aircraft airlines characteristics are different, and the design service life is also different. The market should be cut off exactly, but not be accepted it all. The basal market of China double aisles widebody commercial aircraft is in the zone of China, Asia and the Pacific. In this zone, potential customers should be analyzed carefully, the customers who are not available and also play an important role in this zone should be picked off decisively. The exact market for China double aisles widebody commercial aircraft could reduce engineering difficulties, and also increase airlines adaptability and competition in the specific market zone.