Airport oil depot is an important base for storing aviation fuel．Its safety factors include many aspects．With the safety analysis of airport oil depot, the safety evaluation model of airport oil depot was established by using neural network method．MATLAB software neural network toolbox was used to solve the safety evaluation model and the results are applied to the safety evaluation of the oil depot．The results show that the method agree with the fuzzy comprehensive evaluation method,and the research results have important significance and practical value for the safety monitoring and prediction of oil depots．