CCAR25. 1447( c) (2) ( i) specifies the requirement for the quick donning of crew oxygen masks. Meeting this requirement is very important for airworthiness certification of civil aircraft oxygen system. This paper studies the airworthiness certification requirements of quick donning for crew oxygen masks of civil airplanes. It is analyzed from the aspects of regulation explanation, design and location requirement of crew oxygen masks, airworthiness certification requirements and method of compliance. Requirement for quick donning of crew oxygen masks in regulation is to ensure that flight crew members have necessary anoxic protection in case of emergency and without disturbing the pilot duties of airplane. The certification test method for crew oxygen masks quick donning should show the performance of donning test involving the variable human performance. FAA has some detail requirements for the certification test. Based on this requirement of FAA, this paper summarized a method for compliance certification test of quick donning so as to provide the guidance for compliance certification test of quick donning for crew oxygen masks.