In the development process of civil aircraft avionics system, part number belongs to the category of configuration management, which must be simple, unmatched, and easy to understand. Good part number rules will not only greatly reduce the difficulty of configuration management in independent engineering projects, but also realize the traceability of products through part numbers, which clearly reflect the evolution rules of the company’s product spectrum. This article analyzes part number rules of companies at home and abroad, and summarized the factors that should be paid attention to for different ATA chapters, different kinds of avionics system and equipment part number rules ATA44 Cabin System and ATA 46 Information System were closely combined with internet technology. It is necessary to consider the equipment type spectrum, part number in different layer (equipment, hardware) for different subsystem, different application phenomena and resident software update. Combined with the problems that may be encountered in the typical R&D process of civil aircraft avionics system, the toplevel diagram, equipment nameplate, environmental qualification test, first flight configuration part number management suggestions and aspects needing attention in the whole life cycle of civil avionics system equipment development were given.