This paper describes data check and an inspection procedure for four steps in full-scale Finite Element Analysis (FEA) of aircraft structure, which are FEA model assembling, external loads processing and check, FEM nodes loads generating and typical load cases analysis. Based on strict and timely checking of FEA model and external loads, not only human errors on data processing will be reduced, but also the FEA efficiency of airframe structures will be improved. Furthermore, the capability of aircraft structural strength design will be enhanced as well.