This paper discusses the necessity of establishing design assurance system for domestic civil aircraft manufacturers. The paper introduces the regulatory requirements of Chinese and international airworthiness authorities on design assurance system and analyzes the successful experience of foreign holders on design assurane system establishing. Based on them, ideas and method for China aircraft manufacturers on design assurance system were discussed. The basic frame of design assurance system from design organization manual chapters to procedures list were presented. And some proposals of design assurance system construction were presented ,combined with the current status of domestic design assurance system.