There are mainly two structural connection schemes for connection of aft pressure bulkhead and fuselage on civil aircraft. This paper introduces the structure configuration, advantages and disadvantages of the two connection schemes in detail. The two connection schemes are analyzed and summarized from aspect of the design of OML(outer mold line) surface of the aft pressure bulkhead, the material selection of structure, the weight, the assembly and maintenance space, and the path of system layout planning on pressure bulkhead station. This paper can provide reference for design of the connection between aft pressure bulkhead and fuselage of civil aircraft.